DERIVA CMS contains a combination of Adapalene and Clindamycin, which belongs to the group of medicines called topical retinoids and lincomycin antibiotics. It is used in the treatment of skin acne (pimple). Acne is a condition of the skin when the root of your hair (hair follicle) or skin pores gets clogged by oil or dead skin, which becomes prone to bacterial infection and the formation of pimples, blackheads, spots and scars.

Adapalene is a form of vitamin A, that acts as an antiacne agent by binding directly to the receptor of the skin which increases the rate of cell turnover (cell regeneration) and decreases oil secretion preventing clogging of the hair follicles and pores, also decreasing swelling/inflammation. Clindamycin works by binding to the ribosomal unit of the bacteria and disrupts the production of the protein essential for its survival. Before recommending DERIVA CMS, your doctor may advise you to have tests to understand your existing condition for planning effective treatment methods. Stay well hydrated and protect your skin from exposure to sunlight or UV light.

Do not apply DERIVA CMS if you are allergic to adapalene or clindamycin, a disorder of the digestive system (colitis), a disorder of the immune system or have bruises, cuts or burns on the skin. The common side effects of using this medicine may include dry skin, burning, itching, redness or irritative sensation of the skin, scaling peeling of the skin etc.

USES OF DERIVA CMS

• To treat acne

HOW DERIVA CMS WORKS

Adapalene, a form of vitamin A, works as an antiacne medicine by attaching directly to the skin’s receptor, which increases cell turnover (cell regeneration) and decreases oil secretion preventing blockage of the hair follicles and pores. It also reduces swelling/inflammation of the skin. Clindamycin works by attaching to the bacteria’s ribosomal unit and disrupting the production of a protein required for its very own survival.

DIRECTIONS FOR USE

Apply DERIVA CMS as advised by your doctor. It is for external use on the skin only. Avoid applying DERIVA CMS around or onto your eyes, including eyelids.

SIDE EFFECTS OF DERIVA CMS

HOW TO MANAGE SIDE EFFECTS

Dry Skin:

Drink plenty of water and stay well hydrated. Use moisturizer recommended by your doctor.

WARNING & PRECAUTIONS

INTERACTIONS

A. Drug-Drug interactions:

Inform your physician, if you are taking or using,

• Medicated soap for skin, other cosmetic products with a high concentration of alcohol, astringents, sulfur,
• Resorcinol – use for itching or irritation of the skin and scalp, loss of hair, dandruff etc.
• Salicylic acid – used for skin acne, dandruff, etc.
• Atracurium, cisatracurium, succinylcholine – used to relax muscles

B. Drug-Food interaction:

The interaction of foods with DERIVA CMS is not known. Consult your doctor for diet advice.

Overdosage:

In case of using DERIVA CMS in excess than recommended, you may experience dryness, scaling, redness and discomfort of the skin. Contact your doctor immediately for advice.

SYNOPSIS

MORE INFORMATION

• Keep out of reach from children
• Store at room temperature
• Keep away from sunlight